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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
28.48
Human Site:
S426
Identified Species:
48.21
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S426
D
T
T
T
S
M
H
S
V
E
V
S
G
S
Q
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S426
D
T
I
T
G
M
H
S
V
E
V
S
G
S
Q
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S407
D
T
I
T
G
M
H
S
V
E
V
S
G
S
Q
Dog
Lupus familis
XP_543872
907
102087
S407
D
T
I
T
G
I
H
S
V
E
V
S
G
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S378
D
T
I
T
N
I
H
S
T
E
V
N
G
S
Q
Rat
Rattus norvegicus
XP_001070646
845
94905
R360
L
Q
Y
M
E
R
Y
R
K
R
L
K
A
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S434
D
T
I
T
A
I
H
S
A
E
V
N
G
A
Q
Chicken
Gallus gallus
XP_416375
940
105739
S438
D
T
I
T
C
I
Y
S
A
E
V
S
G
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
S386
D
T
I
S
A
I
H
S
A
E
I
S
G
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
G364
D
S
V
A
Q
L
H
G
S
E
I
S
R
Q
Q
Honey Bee
Apis mellifera
XP_001121183
769
88327
Q317
Y
N
Q
L
C
Q
Y
Q
K
R
F
Q
N
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
Q328
I
L
S
S
W
V
R
Q
L
G
G
R
T
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
T401
E
A
H
N
L
I
E
T
I
N
S
I
Y
S
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
A516
D
A
V
S
N
V
H
A
A
E
I
K
Y
T
D
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
86.6
86.6
80
N.A.
66.6
0
N.A.
60
66.6
N.A.
53.3
N.A.
33.3
0
N.A.
0
P-Site Similarity:
100
86.6
86.6
86.6
N.A.
86.6
13.3
N.A.
86.6
80
N.A.
80
N.A.
53.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
15
0
0
8
29
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
8
0
0
0
8
0
8
0
0
72
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
0
0
22
0
0
8
0
8
8
0
58
8
0
% G
% His:
0
0
8
0
0
0
65
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
50
0
0
43
0
0
8
0
22
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
0
15
0
8
0
% K
% Leu:
8
8
0
8
8
8
0
0
8
0
8
0
0
8
0
% L
% Met:
0
0
0
8
0
22
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
15
0
0
0
0
8
0
15
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
8
8
0
15
0
0
0
8
0
8
65
% Q
% Arg:
0
0
0
0
0
8
8
8
0
15
0
8
8
0
0
% R
% Ser:
0
8
8
22
8
0
0
58
8
0
8
50
0
50
15
% S
% Thr:
0
58
8
50
0
0
0
8
8
0
0
0
8
8
0
% T
% Val:
0
0
15
0
0
15
0
0
29
0
50
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
22
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _